Below are supplemental abstracts and references of research that support the conclusions on the treatment for Asthma

. Diet and Nutrition References


Allergies

Roberts G, et al. "Food allergy as a risk factor for life-threatening asthma in childhood: a case-controlled study." J Allergy Clin Immunol. July,2003;112(1):168-174.

Mairesse M, Ledent C. "Nocturnal asthma due to buckwheat." Revue Francaise D'Allergologie et D'Immunologie Clinique. 2003;43:527-529.

Moneret-Vautrin DA. "Atopy and food allergy." Rev Fr Allergol Immunol Clin. 2000;40:466-472.

Sicherer SH. "Is food allergy causing your patient's asthma symptoms?" J Respir Dis. February. 2000;21(2):127-136.

Platts-Mills TAE, et al. "The relevance of allergen exposure to the development of asthma in childhood." J Allergy Clin Immunol. February,2000;105(2 Part 2):S503-S508.

Baker JC, Ayres JG. "Diet and asthma." Respir Med. 2000;94:925-934.

Karakaya G, et al. "Is there an association between bronchial asthma, food allergy/intolerance and analgesic intolerance?" Eur Respir J. 1999;13:227-228.

Borok G, et al. "Asthma and foods through the ages." S Afric Aller Soc Congress. 1999;1-10.

Jones SM. "The role of food allergy and other allergic disease in atopic dermatitis." Clin Rev Allergy Immunol. 1999;17:293-321.

Sicherer SH, et al. "Food hypersensitivity and atopic dermatitis: pathophysiology, epidemiology, diagnosis, and management." J Allergy Clin Immunol. 1999;104(3part2):S114-S122.

Ziment I. "Can nutritional changes improve asthma symptoms? how your patients may be using diet to treat their asthma." J Resp Dis. November,1998;19(11):999-1006.

Custovic A, et al. "Allergen avoidance in the treatment of asthma and atopic disorders." Thorax. 1998;53:63-72.

Bergmann RL, et al. "Allergen avoidance should be first line treatment for asthma." Eur Resp Rev. 1998;8(53):161-163.

Schiff, M. "Asthma and allergy: which strategy is best?" Emer Med. June,1998;30(6):82-90.

Schaefer OP. "Managing the allergic asthmatic patient." Hosp Med. December,1997;31-46.

James JM, et al. "Wheat ą-amylase inhibitor: a second route of allergic sensitization." J Aller Clin Immunol. 1997;99:239-244.

Bykowski M. "Food allergies can touch off asthma attacks." Skin Aller News. July,1997;21.

James JM. "Food allergy: what link to respiratory symptoms?" J Resp Dis. April,1997;18(4):379-390.

Plaut M. "New directions in food allergy research." J Allergy Clin Immunol. July,1997;100(1):7-10.

Anderson JA. "Food allergy and intolerance." Aller Dis: Diag Treatment. 1997;Chapter15:255-274.

Borok G. "Childhood asthma - foods that trigger." S Afric Med J. June16,1996;77:652.

Warner JO. "Food intolerance and asthma." Clin Exper Allergy. 1995;25(Suppl.1):29-30.

Simon RA. "Food and drug additives." Immunol Allergy Clinics N Am. August,1995;15(3):489-527.

Lessof MH, et al. "Reactions to food additives." Clin Exper Allergy. 1995;25(Suppl.1):27-28.

Chiaramonte LT, Altman D. "Food sensitivity in asthma: perception and reality." J Asthma. 1991;28(1):5-9.

Pelikan Z, Pelikan-Filipek M."Bronchial response to the food ingestion challenge." Ann Allergy. March,1987;58:164-172.

Onorato, Jose, M.D., et al, "Placebo-controlled, double-blind food challenge in asthma." J Allergy Clin Immunol. December,1986;78:1139-1146.

Bock SA. "Food-related asthma and basic nutrition." J Asthma. 1983;20:377-81.

Hoj, et al. "A double-blind controlled trial of elemental diet in severe, perennial asthma." Allergy. 1981;36:257-262.

Oehling A. "Importance of food allergy in childhood asthma." Allergol Immunopathol. 1981;Suppl IX:71-3.

Ogle KA, Bullock JD. "Children with allergic rhinitis and/or bronchial asthma treated with elimination diet: a five-year follow-up." Ann Allergy. 1980;44:273.

Freedman BJ. "A diet free from additives in the management of allergic disease." Clin Allergy. 1977;7:417-21.

Ogle KA, Bullock JD. "Children with allergic rhinitis and/or bronchial asthma treated with elimination diet." Ann Allergy. 1977;39:8.

Freedman BJ. "Asthma induced by sulphur dioxide, benzoate and tartrazine contained in orange drinks." Clin Allergy. 1977;7:407.

Basomba A. "The role of food allergy in children's bronchial asthma." J Asthma Res. 1967;5:129.

Draper WL. "The otolaryngologist and the allergic child." Southern Med J. February,1966;59:217-220.

Rowe AH, et al. "Bronchial asthma due to food allergy alone in ninety-five patients." JAMA. March14,1959;169(11):104/1158-108/1162.


Sulfites and Aspirin

Sen D, et al. "Occupational asthma in fruit salad processing." Clin Exper Aller. 1998;28:363-367.

Peroni DG, Boner AL. "Sulfite sensitivity." Clin Exper Allergy. 1995;25:680-681.

Anibarro B, et al. "Asthma with sulfite intolerance in children: a blocking study with cyanocobalamin." J Allergy Clin Immunol. 1992;90:103-109.

Wright JV. "Defects in sulfur metabolism." Int Clin Nutr Rev. 1989;9(3):118-119.

Wright JV. "Defects in sulfur metabolism. II. Apparent failure of sulphate conjugation." Int Clin Nutr Rev. 1989;9(4):182-184.

Genton C, et al. "Value of oral provocation tests to aspirin and food additives in the routine investigation of asthma and chronic urticaria." Allergy. 1986;41:43-45.

Towns SJ, Mellis CM. "Role of acetyl salicylic acid and sodium metabisulfite in chronic childhood asthma." Pediatrics. May,1984;73(5):631-637.

Papaioannou R, Pfeiffer CC. "Sulfite sensitivity - unrecognized threat: Is molybdenum deficiency the cause?" J Orthomol Psych. 1984;13:105-10.

Jacobsen OW, et al. "Sulfite oxidase deficiency and cobalamin protection in sulfite-sensitive asthmatics (SSA)." J Allergy Clin Immunol. 1984;73:135.

Simon R, et al. "Blocking studies in sulfite sensitive asthmatics (SSA)." J Allergy Clin Immunol. 1984;73:135(Abstract 109).

Stevenson DO, Simon RA. "Sensitivity to ingested metabisulfites in asthmatic subjects." J Allergy Clin Immunol. 1981;68:26.


Dietary Sugar

Kulkarni ML, et al. "Colorings, flavorings, and sugars in children's medicines in India." Br Med J. September25,1993;307:773.

Gumowski P, et al. "Chronic asthma and rhinitis due to Candida albicans, Epidermophyton, and Trichophyton." Annal Allergy. July,1987;59:48-51.


Arachadonic Acid

Bowton DL, et al. "Phospholipase A2 and arachidonate increase in bronchoalveolar lavage fluid after inhaled antigen challenge in asthmatics." Am J Resp Critical Care Med. 1997;155:421-425.

Black PN, Sharpe S. "Dietary fat and asthma: is there a connection?" Eur Resp J. 1997;10:6-12.

Lindahl O, et al. "Vegan regimen with reduced medication in the treatment of bronchial asthma." J Asthma. 1985;22(1):44-55.

Yen SS, Monis HG. "An imbalance of arachidonic acid metabolism in asthma." Biochem Biophys Res Corn. 1981;103:774-9.


EPA

Nagakura T, et al. "Dietary supplementation with fish oil rich in omega-3 polyunsaturated fatty acids in children with bronchial asthma." Eur Respir J. 2000;16:861-865.

Valacer DJ. "Childhood asthma: causes, epidemiological factors and complications." Drugs. 2000;59(Suppl. 1):1-8.

Hodge L, et al. "Consumption of oily fish and childhood asthms risk." MJA. 1996;164:137-140.

Dry J, et al. "Effect of a fish oil diet on asthma: results of a 1-year double-blind study." Int Arch Allergy Apply Immunol. 1991;95:156-157.

Arm JP, et al. "The effects of dietary supplementation with fish oil lipids on the airway response to inhaled allergen in bronchial asthma." Am Rev Resp Dis. 1989;139:1395-1400.

Parm J, et al. "Effect of dietary supplementation with fish oil lipids on mild asthma." Thorax. 1988;43:84-92.


Onions

Dorsch W, et al "Antiasthmatic effects of onions: inhibition of platelet-activating factor-induced bronchial obstruction by onion oils." Intl Archives Aller Appl Immunol. 1987;82:535-536.

Dorsch W, et al. "Antiasthmatic effects of onion extracts - Detection of benzyl- and other isothiocyanates in mustard oils as antiasthmatic compounds of plant origin." Euro J Pharmacol. 1985;107:17-24.

Dorsch W, Weber J. "Prevention of allergen-induced bronchial constriction in sensitized guinea pigs by crude alcohol onion extract." Agents Actions. 1984;14:626-30.

Vanderhoek J, et al. "Inhibition of fatty acid lipoxygenases by onion and garlic oils. Evidence for the mechanism by which these oils inhibit platelet aggregation." Bioch Pharmacol. 1980;29:3169-73.


Vegan diet

Okoko BJ, et al. "Childhood asthma and fruit consumption." Eur Respir J. 2007;29(6):1161-8.

Chatzi L, et al. "Protective effect of fruits, vegetables and the Mediterranean diet on asthma and allergies among children in Crete." Thorax. Apr5,2007

Marz RB. Medical Nutrition from Marz, 2nd ed. Omni Press; Portland, OR; 1997:321.

Lindahl O, et al. "Vegan diet regimen with reduced medication in the treatment of bronchial asthma." J Asthma. 1985;22:45-55.


Caffeine

"Caffeine may help relieve symptoms of hay fever." Fam Prac News. December7,1995;19.

Schwartz J, Weiss ST. "Caffeine intake and asthma symptoms." Annal Epidemiol. 1992;2(5):627-635.

Kivity S, et al. "The effect of caffeine on exercise-induced bronchoconstriction." Chest. 1990;97(5):1083-5.

Pagano R, et al. "Coffee drinking and prevalence of bronchial asthma." Chest. August,1988;94(2):386-389.

Colacone A, et al. "Effect of caffeine on histamine bronchoprovocation in asthma." Thorax. 1990;45:630-632.

Bukowskyj M, Nakatsu K. "The bronchodilator effect of caffeine in adult asthmatics." Am Rev Respir Dis. 1987;135:173-175.

Gong H, et al. "Bronchodilator effects of caffeine in coffee. A dose-response study of asthmatic subjects." Chest. 1986;89(3):1335-42.

Gong H, et al. "Bronchodilator effects of caffeine in coffee. A dose-response study of asthmatic subjects." Chest. March,1986;89(3):335-342.

Becker AB, et al. "The bronchodilator effects and pharmacokinetics of caffeine in asthma." N Eng J Med. 1984;310(12):743-46.

Becker AB, et al. "The bronchodilator effects and pharmacokinetics of caffeine in asthma." New Eng J Med. March22,1984;310(12):743-746.


Vitamin and Mineral References


Beta-carotene and Vitamin A

Neuman I, et al. "Prevention of exercise-induced asthma by a natural isomer mixture of beta-carotene." Ann Allergy Asthma Immunol. June,1999;82:549-553.

Baker JC, et al. "Dietary antioxidants and magnesium in type 1 brittle asthma: a case control study." Thorax. 1999;54:115-118.

Trenga CA, et al. "Sulfur dioxide sensitivity and plasma antioxidants in adult subjects with asthma." Occup Environ Med. 1999;56:544-547.

Broughton KS, et al. "Reduced asthma symptoms with n-3 fatty acid ingestions are related to 5-series leukotriene production." Am J Clin Nutr. 1997;65:1011-17.

Grosch W, et al. "Co-oxidation of carotenes requires one soy bean lipoxygenase isoenzyme." Biochem Biophys Acta. 1979;575:439-445.


Vitamin B6

Sur S, et al. "Double-blind trial of pyridoxine (vitamin B6) in the treatment of steroid-dependent asthma." Ann Allergy. 1993;70:147-152.

Delport R, et al. "Vitamin B6 nutritional status in asthma: the effect of theophylline therapy on plasma pyridoxal-5'-phosphate and pyridoxal levels." Int J Vitam Nutr Res. 1988;58(1):67-72.

Reynolds RD, Natta CL. "Depressed plasma pyridoxal phosphate concentrations in adult asthmatics ." Am J Clin Nutr. April,1985;41:684-688.

Collipp PJ. "Pyridoxine treatment of childhood bronchial asthma." Annals of Allergy. 1975,August;35:93-97.


Vitamin B12

Wright JV. "Treatment of childhood asthma with parenteral vitamin B12, gastric re-acidification, and attention to food allergy, magnesium and pyridoxine: three case reports with background and an integrated hypothesis." J Nutr Med. 1990;1:277-282.

Wright JV. "Vitamin B12: powerful protection against asthma." Int Clin Nutr Rev. 1989;9(4):185-188.

Crocket JA. "Cyanocobalamin in asthma." Acta Allergologica. 1957;11:261.

Caruselli M. "Vitamin B12 in asthma." Riforma Medica. August 2, 1952;66:841-864.

Simon. "Vitamin B12 therapy in allergy and chronic dermatosis." J Aller. 1951;2:183-5.

Kaufman RE. "Effect of vitamin B12 in asthma." Ann Allergy. 1951;9:517.

Wetzel NC, et al. "Growth failure in school children as associated with vitamin B12 deficiency: response to oral therapy." Science. 1949;110:651.


Vitamin C

Tecklenburg SL, et al. "Ascorbic acid supplementation attenuates exercise-induced bronchoconstriction in patients with asthma." Respir Med. Apr4,2007

Patel BD, et al. "Dietary antioxidants and asthma in adults." Thorax. 2006;61(5):388-93.

Misso NL, et al. "Plasma concentrations of dietary and nondietary antioxidants are low in severe asthma." Eur Respir J. 2005;26(2):257-64.

Gyorik SA, Brutsche MH. "Complementary and alternative medicine for bronchial asthma: is there new evidence?" Curr Opin Pulm Med. 2004;10:37-43.

Picado C, et al. "Dietary micronutrients/antioxidants and their relationship with bronchial asthma severity." Allergy. 2001;56:43-49.

Forastiere F, et al. "Consumption of fresh fruit rich in vitamin C and wheezing symptoms in children." Thorax. 2000;55:283-288.

Fogarty A, et al. "The role of diet in the aetiology of asthma." Clin Exp Allergy. 2000;30:615-627.

Greene LS. "Asthma, oxidant stress, and diet." Nutr. 1999;15(11/12):899-907.

van Schayck CP, et al. "Are anti-oxidant and anti-inflammatory treatments effective in different subgroups of COPD? a hypothesis." Respir Med. November,1998;92(11):1259-1264.

Cohen HA, et al. "Blocking effect of vitamin C in exercise-induced asthma." Arch Ped Adolesc Med. April,1997;151:367-370.

Soutar A, et al. "Bronchial reactivity and dietary antioxidants," Thorax. February,1997;52(2):166-170.

Hatch GE. "Vitamin C and asthma." Vitamin C in Health and Disease, Packer, Lester and Fuchs, Jurgen, eds. 1997;Chapter 15:279-294.

Greene LS. "Asthma and oxidant Stress: nutritional, environmental and genetic risk factors." J Am Coll Nutr. 1995;14(4):317-324.

Hatch GE, et al. "Asthma, inhaled oxidants and dietary antioxidants." Am J Clin Nutr. 1995;61(Suppl.):625S-630S.

Bielory L, Gandhi R. "Asthma and vitamin C." Annal Allergy. August,1994;73:89-96.

Schwartz J, Weiss ST. "Relationship between dietary vitamin C intake and pulmonary function in the First National Health and Nutrition Examination Survey (NHANES I)." Am J Clin Nutr. 1994;59:110-4.

Rolla G, et al. "Hypomagnesemia in chronic obstructive lung disease: effect of therapy." Magnes Trace Elem. 1990;9(3):132-136.

Bucca C, et al. "Effect of ascorbic acid on increased bronchial responsiveness during upper airway infection." Resp. 1989;55:214-219.

Fiaccadori E, et al. "Muscle and serum magnesium in pulmonary intensive care unit patients." Crit Care Med. August,1988;16(8):751-760.

Aderele WI, et al. "Plasma vitamin C (ascorbic acid) levels in asthmatic children." Afric J Med Medical Sci. 1985;14:115-120.

Anderson R, et al. "Ascorbic acid in bronchial asthma." SA Med J. 1983;63:649-52.

Spannhake EW, Menkes HA. "Vitamin C - New tricks for an old dog." Am Rev Resp Dis. 1983;127:139-41.

Mohsenin V, et al. "Effect of ascorbic acid on response to methylcholine challenge in asthmatic subjects." Am Rev Respir Dis. 1983;127:143-7.

Schachter EN, Schlesinger A. "The attenuation of exercise-induced bronchospasm by ascorbic acid." Annal Allergy. September,1982;49:146-151.

Anah CO, et al. "High dose ascorbic acid in Nigerian asthmatics." Trop Geogr Med. 1980;32:132-7.

Olusi SO, et al. "Plasma and white blood cell ascorbic acid concentrations in patients with bronchial asthma." Clinica Chimica Acta. 1979;92:l6l-6.

Buck MG, Zadunaisky JA. "Stimulation of ion transport by ascorbic acid through inhibition of 3':5'-cyclic-AMP phosphodiesterase in the corneal epithelium and other tissues." Biochemica Biosphysica Acta. 1975;389:251-60.


Magnesium

Gontijo-Amaral C, et al. "Oral magnesium supplementation in asthmatic children: a double-blind randomized placebo-controlled trial." Eur J Clin Nutr. Jun21,2006

Ciarallo L, et al. "Higher-dose intravenous magnesium therapy for children with moderate to severe acute asthma." Arch Pediatr Adolesc Med. 2000;154:979-983.

Rowe BH, et al. "Magnesium sulfate is effective for severe acute asthma treated in the emergency department." WJM. February. 2000;172:96.

Nannini LJ, et al. "Magnesium sulfate as a vehicle for nebulized salbutamol in acute asthma." Am J Med. February15,2000;108:193-197.

Dib JG, et al. "Intravenous magnesium sulfate treatment in a child With status asthmaticus." Am J Health-Syst Pharm. May15,1999;56:997-1000.

Rowe BH, et al. "Magnesium sulfate treatment for acute asthmatic exacerbations treated in the emergency department." Cochrane Rev. February23,1999.

Swain R, Kaplan-Machlis B. "Magnesium for the next millennium." South Med J. November,1999;92(11):1040-1047.

Harari M, et al. "Magnesium in the treatment of asthma: critical review of acute and chronic treatments, and Deutsches Medizinisches Zentrum's (DMZ's) clinical experience at the Dead Sea." J Asthma. 1998;35(7):525-536.

Mangat HS, et al. "Nebulized magnesium sulfate versus nebulized salbutamol in acute bronchial asthma: a clinical trial." Eur Resp J. 1998;12:341-344.

Nannini LJ, Hofer D. "Effect of inhaled magnesium sulfate on sodium metabisulfite-induced bronchoconstriction in asthma." Chest. April,1997;111(4):858-861.

Cairns CB, Kraft M. "Magnesium attenuates the neutrophil respiratory burst in adult asthmatic patients." Acad Emerg Med. 1996;3:1093-1097.

Ciarallo L, et al. "Intravenous magnesium therapy for moderate to severe pediatric asthma: results of a randomized, placebo-controlled trial." J Pediatr. December,1996;129(6):809-814.

Durlach J. "Magnesium depletion, magnesium deficiency and asthma." Magnesium Res. 1995;8(4):403-405.

Britton J, et al. "Dietary magnesium, lung function, wheezing and airway hyper- reactivity in a random adult population sample." Lancet. August6,1994;344:357-362.

Seelig MS, et al. "Consequences of magnesium deficiency on enhancement of stress reaction; preventive and therapeutic implications (a review)." J Am Coll Nutr. 1994;13(5):429-446.

McLean RM. "Magnesium and its therapeutic uses: a review." Am J Med. January,1994;96:63-76.

Landon RA, Young EA. "Role of magnesium in regulation of lung function." J Am Diet Assoc. June,1993;93(6):674-677.

Okayama H, et al. "Treatment of status asthmaticus with intravenous magnesium sulfate." J Asthma. 1991;28:11-17.

Neves MC, et al. "Evaluation of Mg2+ aspartate HCl in asthmatic crises." Mag Bull. 1991;13(3):88-92.

Skobeloff EM, et al. "Intravenous magnesium sulfate for the treatment of acute asthma in the emergency department." JAMA. 1989;262:1210-1213.

Rolla G, et al. "Acute effect of intravenous magnesium sulfate on airway obstruction of asthmatic patients." Annal Allergy. November,1988;61:388-391.

Okayama H, et al. "Bronchodilating effect of intravenous magnesium sulfate in bronchial asthma." JAMA. 1987;February 27;257(8):1076-1078.

Brunner EH, et al. "Effect of parenteral magnesium on pulmonary function, plasma cAMP, and histamine in bronchial asthma." J Asthma. 1985;22: 3-11.

Haury VG. "Blood serum magnesium in bronchial asthma and its treatment by the administration of magnesium sulfate." J Lab Clin Med. 1940;26:340-344.


Molybdenum

Marz RB. Medical Nutrition from Marz, 2nd ed. Omni Press; Portland, OR; 1997:322.

Wright J, et al. "Defects in sulphur metabolism." Int Clin Nutr Rev. 1989;9(3):118-119.

Papaioannou R, et al. "Sulfite sensitivity - unrecognized threat: Is molybdenum the cause?" J Orthomol Psychiatry. 1984;13(2):105-110.


Selenium

Kadrabova J, et al. "Selenium status is decreased in patients with intrinsic asthma." Biol Trace Element Res. 1996;52:241-248.

Misso NLA, et al. "Reduced platelet glutathione peroxidase activity and serum selenium concentration in atopic asthmatic patients." Clin Exp Allergy. 1996;26:838-847.

Stone J, et al. "Reduced selenium status of patients with asthma." Clin Sci. 1989;77:495-500.


Supplement References


N-Acetyl Cysteine

Volkl KP, Schneider B."Therapy of respiratory tract diseases with N-acetylcysteine. an open therapeutic observation study of 2,512 patients." Fortschr Med. June30,1992;110(18):346-350.

Braverman ER, et al. The Healing Nutrients Within. Keats Publishing; New Canaan, CT; 1987.

Bylin G, et al. "No influence of acetylcysteine on gas exchange and spirometry in chronic asthma." Eur J Resp Dis. 1987;71:102-107.

Millman M, et al. "Use of acetyleysteine in bronchial asthma - another look." Ann Allergy. 1985;54:269-6.


Omega-3 Fatty Acid

Miyamoto S, et al. "Fat and fish intake and asthma in Japanese women: baseline data from the Osaka Maternal and Child Health Study." Int J Tuberc Lung Dis. 2007;11(1):103-9.

Mickleborough TD, Lindley MR. "Protective effect of fish oil supplementation on exercise-induced bronchoconstriction in asthma." Chest. 2006;129(1):39-49.

Mickleborough TD, Rundell KW. "Dietary polyunsaturated fatty acids in asthma- and exercise-induced bronchoconstriction." Eur J Clin Nutr. 2005;59(12):1335-46.

Wong KW. "Clinical efficacy of n-3 fatty acid supplementation in patients with asthma." J Am Diet Assoc. Jan,2005;105(1):98-105.

Prescott SL, Calder PC. "N 3 polyunsaturated fatty acids and allergic disease." Curr Opin Clin Nutr Metab Care. 2004;7:123-129.

Calder PC, Miles EA. "Fatty acids and atopic disease." Pediatr Allergy Immunol. 2000;(Suppl. 13):29-36.

Okamoto M, et al. "Effects of dietary supplementation with n-3 fatty acids compared with n-6 fatty acids on bronchial asthma." Intern Med. February,2000;39(2):107-111.

Masuev KA. "The effect of polyunsaturated fatty acids on the biochemical indices of bronchial asthma patients." Ter Arkh. 1997;69(3):33-35.

Broughton KS, et al. "Reduced asthma symptoms with n-3 fatty acid ingestion are related to 5-series leukotriene production." Am J of Clin Nutr. 1997;65:1011-1017.

Hodge L. "Consumption of oily fish and childhood asthma risk." Med J Australia. 1996;164:137-140.

Thien FCK, et al. "Oily fish and asthma - a fishy story?" Med J Austral. February5,1996;164:135-136.

Dry J, Vincent D. "Effects of a fish oil diet on asthma: results of a one-year double-blind study." Intl Arch Allergy Applied Immunol. 1991;95:156-157.


Quercetin

Foreman JC. "Mast cells and the actions of flavonoids." J Aller Clin Immunol. 1984;73:769-74.

Hope WC, et al. "In vitro inhibition of the biosynthesis of slow reacting substance of anaphylaxis (SRS-A) and lipoxygenase activity by quercetin." Biochem Pharmacol. 1983;32:367-71.

Middleton E, et al. "Quercetin: An inhibitor of antigen-induced human basophil histamine release." J Immunol. 1981;127:546-50.

Fewtrell CMS, Gomperts BD. "Effect of flavone inhibitors of transport ATPase on histamine secretion from rat mast cells." Nature. 1977; 265:635-6.


Hydrochloric Acid

Bray GW. "The hypochlorhydria of asthma in childhood." J Nutr Med. 1990;1:347-360/Quarterly J Med. 1931;24:181-197.


Coenzyme Q10

Gvozdjakova A, et al. "Coenzyme Q-10 supplementation reduces corticosteroids dosage in patients with bronchial asthma." Biofactors. 2005;25(1-4):235-40.


Botanical References


Urtica urens, Euphrasia officinalis, Eriodictyon californicum, Astragalus membranaceus, Bupleurum chinense, Inula helenium, Zea mays, Verbascum thapsus, Armoracia rusticana

Mitchell WA. Plant Medicine. Preparatory Manuscript; Seattle, WA; 2000.

Bielory L, Lupoli K. "Herbal interventions in asthma and allergy." J Asthma. 1999;36(1):1-65.

Tilgner S. Herbal Medicine-From the Heart of the Earth. Wise Acres Press, Inc.; Creswell, OR; 1999.

Ziment I. "How your patients may be using herbalism to treat their asthma." J Resp Dis. December,1998;19(12):1070-1081.

Ogletree RL, Rischer RG. Physician's and Pharmacist's Guide to the Top 10 Scientifically Proven Natural Products. Natural Source Digest; 2nd Ed. Brandon, MS; 1997.

Chevallier A. The Encyclopedia of Medicinal Plants. DK Publishing; New York, NY; 1996:55.

Murray MT. The Healing Power of Herbs. 2nd Ed. Prima Publishing; Rocklin, CA; 1995.

Ellingwood F. American Materia Medica, Therapeutics and Pharmacognosy; Botanical Vol. II. Eclectic Medical Publications; Sandy, OR; 1994.

Felter HW. The Eclectic Materia Medica, Pharmacology and Therapeutics, Botanical Vol. 1. Eclectic Medical Publications; Sandy, OR; 1994.

Scalzo R. Naturopathic Handbook of Herbal Formulas. 3rd Ed. Kivaki Press; Durango, CO; 1994.

Ody P. The Complete Medicinal Herbal. Dorling Kindersley; New York, NY; 1993.

Stansbury JE. Botanical Medicines Acting on the Respiratory System. Preparatory Manuscript; Battleground, WA; 1992.

Stansbury JE. Pharmacognosy for the Herbal Practitioner. Preparatory Manuscript; Battleground, WA; 1992.

Thomas L. 10 Essential Herbs. Hohm Press; Prescott, AZ; 1992.

Weiss RF. Herbal Medicine. Beaconsfield Publishers LTD; Beaconsfield, England; 1991.

Hoffman, D. The New Holistic Herbal. Element Inc; Rockport, MA; 1991.

Mabey R, et al. The New Age Herbalist. Collier Books, Macmillan Publishing Company; New York, NY; 1988. England;1988.

Tyler VE, et al. Pharmacognosy. 9th Ed. Lea & Febiger; Philadelphia, PA; 1988.

Wren RC. Potter's New Cyclopaedia of Botanical Drugs and Preparations. The C.W. Daniel Company Limited; Essex; 1988

Carr A, et al. Rodale's Illustrated Encyclopedia of Herbs. Rodale Press; Emmaus, PA; 1987.

Mowrey DB. The Scientific Validation of Herbal Medicine. Keats Publishing, Inc.; New Canaan, CT; 1986.

Beyer P. The Master Book of Herbalism. Phoenix Publishing; Custer, WA; 1984.

Goodenough J. Dr. Goodenough's Home Cures & Herbal Remedies. Avenel Books; New York, NY; 1982.

Millspaugh CF. American Medicinal Plants. Dover Publications, Inc.; New York, NY; 1974.

Grieve M. A Modern Herbal. Vol. I & II; Dover Publications, Inc.; New York, NY; 1971.


Homeopathy References


Morrison R.Desktop Guide to Keynotes and Confirmatory Symptoms.Hahnemann Clinic Publishing; Albany, CA; 1993.

Murphy R.Homeopathic Medical Repertory.Hahnemann Academy of North America; Pagosa Springs, CO; 1993.

Phatak SR. A Concise Repertory of Homoeopathic Medicines. B. Jain Publishers Pvt. Ltd.; New Delhi, India; 1992.

Kruzel T. The Homeopathic Emergency Guide.North Atlantic Books; Berkeley, CA; 1992.

Kent JT. Repertory of the Homeopathic Materia Medica.B. Jain Publishers (P) LTD; New Delhi, India; 1991.

Boericke W. Materia Medica with Repertory, 9th Ed..Boericke & Tafel, Inc.; Santa Rosa, CA; 1927.


Other Treatment References


Repair Intestinal Mucosa

Hijazi Z, et al. "Intestinal permeability is increased in bronchial asthma." Arch Dis Child. 2004;89:227-229.

Isolauri E. "Intestinal involvement in atopic disease." J Royal Soc Med. 1997;90(Suppl.30):15-20.

Benard A, et al. "Increased intestinal permeability in bronchial asthma." J Allergy Clin Immunol. June,1996;97(6):1173-1178.

Akiyama K, et al. "Atopic asthma caused by Candida albicans acid protease: case reports." Allergy. 1994;49:778-81.


Hydrogen Peroxide Bath

Burton Goldberg Group. Alternative Medicine: The Definitive Guide. Future Medicine Publishing, Inc. Puyallup, WA.1994;p.819.


Antibiotics

Wickens K, et al. "Antibiotic use in early childhood and the development of asthma." Clin Exp Allergy. 1999;29:766-771.


Exercise

Hallstrand TS, et al. "Aerobic conditioning in mild asthma decreases the hyperpnea of exercise and improves exercise and ventilatory capacity." Chest. November,2000;118(5):1460-1469.

Disabella V. "Exercise for asthma patients: little risk, big rewards." Phys Sportsmed. June,1998;26(6):75-84.

Kuehl KS and Goldberg L. "Asthma and exercise in the elderly." Treatment Asthma Aller Dis Elder. November,1997;17(4):607-626.

Thomas AE, Woodfolk JA. "Rise in asthma cases." Sci. November7,1997;278:1001.

Prefaut CH, et al. "Value of sport in asthmatics." Rev Fr Allergol. 1996;36(3):254-258.

Jain SC, et al. "Effect of yoga training on exercise tolerance in adolescents with childhood asthma." J Asthma. 1991;28(6):437-442.


Traffic Density and Air Pollution

Hoppin JA, et al. "Diesel exhaust, solvents, and other occupational exposures as risk factors for wheeze among farmers." Am J Respir Crit Care Med. 2004;169:1308-1313.

Kelly FJ. "Oxidative stress: its role in air pollution and adverse health effects." Occup Environ Med. 2003;60:612-616.

Kirn TF. "Greenland study links atopy to urbanization." Skin Allergy News. April,2001;40.

Friedman MS, et al. "Impact of changes in transportation and commuting behaviors during the 1996 summer olympic games in Atlanta on air quality in childhood asthma." JAMA. February21,2001;285(7):897-905.

Roemer W, et al. "Pollution effects on asthmatic children in Europe, the Peace Study." Clin Exp Allergy. 2000;30:1067-1075.

Koenig JQ. "Air pollution and asthma." J Allergy Clin Immunol. October,1999;104(4part1):717-722.

Steerenberg PA, et al. "Environmental and lifestyle factors may act in concert to increase the prevalence of respiratory allergy including asthma." Clin Exp Allergy. 1999;29:1304-1308.

de Diego DA, et al. "Effects of air pollution and weather conditions on asthma exacerbation." Respiration. 1999;66:52-58.

Forsberg B, et al. "Daily air pollution levels and acute asthma in southern Sweden." Eur Resp J. 1998;12:900-905.

Le Roux P, et al. "Asthma in children, acute effects of air pollution: an epidemiological study in Le Havre area." Revue Franc DžAllergologie. 1997;37(2):176-182.

Lipsett M, et al. "Air pollution and emergency room visits for asthma in Santa Clara County, California." Envir Health Perspectives. February,1997;105(2):216-222.

Koren HS, Utell MJ. "Asthma and the environment." Envir Health Perspectives. May,1997;105(5):533-537.

Forsberg B, et al. "People can detect poor air quality well below guideline concentrations: a prevalence study of annoyance reactions and air pollution from traffic." Occup Environ Med. January,1997;54(1):44-48.

"The association between self- reported symptoms of asthma and allergic rhinitis and self- reported traffic density on street of residence in adolescents." Epidemiol. 1996;7:578-582.

Flodin U, et al. "Bronchial asthma and air pollution at workplaces." Scand J Work Environ Health. 1996;22:451-456.

Peters A, et al. "Acute health effects of exposure to high levels of air pollution in eastern Europe." Am J Epidemiol. 1996;144(6):570-581.

Bascom R. "Health effects of outdoor air pollution." Am J Respiratory Crit Care Med. 1996;153:3-50.

Taggart SCO, et al. "Asthmatic bronchial hyperresponsiveness varies with ambient levels of summertime air pollution." Eur Resp J. 1996;9:1146-1154.

Romieu I, et al. "Effects of air pollution on respiratory health of asthmatic children living in Mexico City." Am J Resp Critical Care Med. 1996;154:300-307.

Ostro BD, et al. "Air pollution and asthma exacerbations among African-American children in Los Angeles." Inhal Toxicol. 1995;7:711-722.

Walters S, et al. "Hospital admission rates for asthma and respiratory diseases in West Midlands: their relationship to air pollution levels." Thorax. 1995;50:948-954.

Newman-Taylor A. "Environmental determinants of asthma." Lancet. February4,1995;345:296-299.

Burr ML. "Pollution: does it cause asthma?" Arch Dis Children. 1995;72:377-387.

Tseng R, et al. "Particulate air pollution and hospitalization for asthma." Annal Allergy. May,1992;68:425-432.


Smoking

Agabiti N, et al. "The impact of parental smoking on asthma and wheezing." Epidemiol. November,1999;10(6):692-698.

Sasaki H, et al. "Effects of air pollution and smoking on chronic obstructive pulmonary disease and bronchial asthma." Tohoku J Exp Med. 1998;186:151-167.

Kimber I. "Allergy, asthma and the environment: an introduction." Toxicol Lett. 1998;102-103:301-306.

Abulhosn RS, et al. "Passive smoke exposure impairs recovery after hospitalization for acute asthma." Arch Ped Adolesc Med. February,1997;151:135-139.

Stick SM, et al. "Effects of maternal smoking during pregnancy and a family history of asthma on respiratory function in newborn infants." Lancet. October19,1996;348:1060-1064.

Murray A, et al. "The decrease in severity of asthma in children of parents who smoke since the parents have been exposing them to less cigarette smoke." J Aller and Clin Immunol. 1993;January:91(1/PartI):102-110.

Weiss ST. "Environmental tobacco smoke and asthma." Chest. October,1993;104(4):991-992.

Chilmonczyk BA, et al. "Association between exposure to environmental tobacco smoke and exacerbations of asthma in children." New Eng J Med. June10,1993;328(23):1665-1669.

"Secondhand cigarette smoke worsens asthma in children." Fam Prac News. April15-30,1987.


Damp Surroundings

Norback D, et al. "Current asthma and biochemical signs of inflammation in relation to building dampness in dwellings." Intl J Tuberc Lung Dis. 1999;3(5):368-376.

Eggleston PA, et al. "Environmental allergen avoidance in allergic asthma." J Aller Clin Immunol. February,1999;103:203-205.

Yang C-Y, et al. "Indoor environmental risk factors and childhood asthma: a case- control study in a subtropical area." Pediatr Pulmonol. 1998;26:120-124.


Obesity

Hong SJ, et al. "High body mass index and dietary pattern are associated with childhood asthma." Pediatr Pulmonol. 2006;41(12):1118-24.


Thyroid Panel

Anderson CJ. "Endocrinopathies masquerading as allergic diseases; thyroid disease: the great pretender." Immunol Allergy Clinics N Am. February,1996;16(1):107-117.

Copyright 1998 - 2008 by L. Vicky Crouse, ND and James S. Reiley, ND. All rights reserved (ISSN 1527-0661).