Below are supplemental abstracts and references of research that support the conclusions on the treatment for Attention Deficit Disorder

. Diet and Nutrition References


Food Allergies

Schimdt MH, et al. "Does oligoantigenic diet influence hyperactive/conduct-disordered children--a controlled trial." Eur Child Adolesc Psychiatry. June,1997;6(2):88-95.

Egger J, et al. "Controlled trial of oligoantigenic treatment in the hyperkinetic syndrome." Lancet. March9,1985:540-546.

Hindle RC, et al. "The management of hyperkinetic children: a trial of dietary therapy." NZ Med J. July26,1978;616(88):43-45.


Food Additives

Bateman B, et al. "The effect of a double blind, placebo controlled, artificial food colourings and benzoate preservative challenge on hyperactivity in a general population sample of preschool children." Arch Dis Child. June,2004;89:506-511.

Lessof MH, et al. "Reactions to food additives." Clin Exper Allergy. 1995;25(Suppl.1):27-28.

Boris M, Mandel FS. "Food and additives are common causes of the attention deficit hyperactive disorder in children." Annals of Aller. 1994;May,72:462-468.

Rowe KS, et al. "Synthetic food coloring and behavior: a dose response effect in a double-blind, placebo-controlled, repeated-measures study." J Ped. 1994;125(5part1):691-698.

Gibb C, et al. "Inhibition of phenolsulphotransferase P by certain food constituents." Lancet. 1986;1:794.

NIH Consensus Development Conference. "Defined diets and childhood hyperactivity." Clin Ped. 1982;21:627.

Ribon A, Joshi S. "Is there any relationship between food additives and hyperkinesis?" Ann Aller. 1982;48:275.

Mattes JA, Gittelman R. "Effects of artificial food colorings in children with hyperactive symptom." Arch Gen Psych. 1981;38:714.

Rippere V. "Placebo-controlled tests of chemical food additives: are they valid?" Med Hypotheses. 1981;7:819.

Weiss B, et al. "Behavioral responses to artificial food colors." Science. 1980;207:1487.

Swanson JM, Kinsbourne M. "Food dyes impair performance of hyperactive children on a laboratory learning test." Science. 1980;207:1485.

Connors CK, et al. "Dose-time effect of artificial colors in hyperactive children." J Learning Dis. 1980;131:512.

Harley JP, et al. "Synthetic food colors and hyperactivity in children: a double-blind challenge experiment." Ped. 1978;62:975.

Levy F, et al. "Hyperkinesis and diet: a double-blind crossover trial wtih a tartrazine challenge." Med J Aust. January28,1978;1(2):61-64.

Harley JP, et al. "Hyperkinesis and food additives: testing the Feingold hypothesis." Ped. June,1978;61(6):818-828.

Williams JI, et al. "Relative effects of drugs and diet on hyperactive behaviors: an experimental study." Ped. 1978;61:811.

Williams JI, Cram DM. "Diet in the management of hyperkinesis: a review of the tests of Feingold's hypotheses." Can Psychiatr Assoc J. 1978;23:241-248.

Harper PH, et al. "Nutrient intakes of children on the hyperkinesis diet." J Am Diet Assoc. 1978;73:515.

Brenner A. "A study of the efficacy of the Feingold diet on hyperkinetic children: some favorable personal observations." Clin Ped. 1977;16:652.

Feingold BF. "Hyperkinesis and learning disabilities linked to the ingestion of artificial food colors and flavors." J Learn Disabil. November,1976;9(9):19-27.

Connors CK, et al. "Food additives and hyperkinesis: a controlled double-blind experiment." Ped. 1976;58:154.


Simple Sugars

Goldman JA, et al. "Behavioral effects of sucrose on preschool children." J Abnorm Child Psychol. 1986;14(4):565-577.

Egger J, et al. "Controlled trial of oligoantigenic treatment in the hyperkinetic syndrome." Lancet. 1985;540-545.

Prinz R, et al. "Dietary correlates of hyperactive behavior in children." J Consult Clin Psych. 1980;48:760-9.

Langseth L, et al. "Glucose tolerance and hyperkinesis." Food Cosmet Toxicol. 1978;16:129-33.


Vitamin and Mineral References


Vitamin B6 and Nicotinamide

Brenner A. "The effects of megadoses of selected B complex vitamins on children with hyperkinesis: controlled studies with long-term follow-up." J Learn Disabil. May,1982;15(5):258-264.

Coleman M, et al. "A preliminary study of the effect of pyridoxine administration in a subgroup of hyperkinetic children: a double-blind crossover comparison with methylphenidate." Biol Psych. 1979;14:741.

Coleman M, et al. "The role of whole blood serotonin levels in monitoring vitamin B6 and drug therapy in hyperactive children." Agents Actions. 1975;5:496.

Hoffer A. "Treatment of hyperkinetic children with nicotinamide and pyridoxine." Can Med Assoc J. 1972;107:111.


Vitamin C

Joshi K, et al. "Supplementation with flax oil and vitamin C improves the outcome of Attention Deficit Hyperactivity Disorder (ADHD)." Prostaglandins Leukot Essent Fatty Acids. Nov25,2005.

Papaioannou R, et al. "Reduction of blood lead levels in battery workers by zinc and vitamin C." J Qrthomolec Psych. 1978;7:94.

Sohler A, et al. "Blood lead levels in psychiatric outpatients reduced by zinc and vitamin C." J Orthomolec Psych. 1977;6:272.

Mahaftey KR, Banks TA. "Effect of varying dietary ascorbic acid (AA) on lead (Pb) toxicity in guinea pigs." Fed Proc. 1975;34:267.

Fox MRS. "Protective effects of ascorbic acid against toxicity of heavy metals." Ann NY Acad Sci. 1975;258:144.

Suzuki T, Yoshida A. "Effectiveness of dietary iron and ascorbic acid in the prevention and cure of moderately long-term lead toxicity in rats." J Nutr. 1979;109:1974.

Kubala AL, Katz MM. "Nutritional factors in psychological test behavior." J Genet Psychol. 1960;96:343-352.


Zinc

Rimland B, et al. "Zinc aids ADHD kids." Prog Neuropsychopharmacol Bio Psychiatry. Jan,2004;28(1):181-190.

Sandyk R. "Zinc deficiency and cerebellar disease." Intl J Neurosci. 1991;60:21-26.

Ward NI, et al. "The influence of the chemical additive tartrazine on the zinc status of hyperactive children - a double-blind placebo-controlled study." J Nutr Med. 1990;1:51-57.

Sandstead HH. "A brief history of the influence of trace elements on brain function." J Clin Nutr. February,1986;43:293-298.


Calcium

Marz RB. Medical Nutrition from Marz, 2nd ed. Omni Press; Portland, OR; 1997:315.


Magnesium

Mousain-Bosc M, et al. "Improvement of neurobehavioral disorders in children supplemented with magnesium-vitamin B6. II. Pervasive developmental disorder-autism." Magnes Res. 2006;19(1):46-52.

Liebscher D-H, Liebscher D-E. "About the misdiagnosis of magnesium deficiency." J Am Coll Nutr. 2004;23(6):730S-731S.

"Magnesium reduces hyperactivity." Autism Res Rev Intl. 1998;12(2):4.

Starobrat-Hermelin B, Kozielec T. "The effects of magnesium physiological supplementation on hyperactivity in children with attention deficit hyperactivity disorder (ADHD). Positive response to magnesium oral loading test," Magnesium Res. 1997;10(2):149-156.

Kozielec T, Starobrat-Hermelin B. "Assessment of magnesium levels in children with attention deficit hyperactivity disorder (ADHD)." Magnesium Res. 1997;10(2):143-148.


Supplement References


Fatty Acids

Peet M, Stokes C. "Omega-3 fatty acids in the treatment of psychiatric disorders." Drugs. 2005;65(8):1051-1059.

Richardson AJ. "Long-chain polyunsaturated fatty acids in childhood developmental and psychiatric disorders." Lipids. Dec,2004;39(12):1215-1222.

Burgess JR, et al. "Long-chain polyunsaturated fatty acids in children with attention-deficit hyperactivity disorder." Am J Clin Nutr. 2000:71(Suppl):327S-330S.

Wright T, et al. "Docosahexaenoic acid-enriched milk." Return Omega-3 Fatty Acids Food Supply. 1998;83:160-165.

Bekaroglu M, et al. "Relationships between serum free fatty acids and zinc, and attention deficit hyperactivity disorder: a research note." J Child Psychol Psychiatr. 1996;37(2):225-227.

Aman MG, et al. "The effects of essential fatty acid supplementation by efamol in hyperactive children." J Abnorm Child Psychol. 1987;15(1):75-90.

Mitchell EA, et al. "Clinical characteristics and serum essential fatty acid levels in hyperactive children." Clin Pediatr. August,1987;26(8):406-411.

Stevens LJ. et al. "Essential fatty acid metabolism in boys with attention-deficit hyperactivity disorder." Am J Clin Nutr. 1995;62:761-8.

Colquhoun, Bunday. "A lack of EFA as a possible cause of hyperactivity in children." Med Hypothesis. 1981;7:673-979.


Pycnogenol

Trebaticka J, et al. "Treatment of ADHD with French maritime pine bark extract, Pycnogenol((R))." Eur Child Adolesc Psychiatry. May13,2006.


Botanicals References


Passiflora incarnata, Melissa officinalis, Nepeta cataria, Eschscholzia californica, Lavendula angustifolia

Mitchell WA. Plant Medicine. Preparatory Manuscript; Seattle, WA; 2000.

Tilgner S. Herbal Medicine-From the Heart of the Earth. Wise Acres Press, Inc.; Creswell, OR; 1999.

Wong AHC, et al. "Herbal remedies in psychiatric practice." Arch Gen Psychiatry. November,1998;55:1033-1044.

Balch JR, et al. Prescription for Nutritional Healing, 2nd ed. Avery Press; NY, NY; 1997:330.

Ogletree RL, Rischer RG. Physician's and Pharmacist's Guide to the Top 10 Scientifically Proven Natural Products. Natural Source Digest; 2nd Ed. Brandon, MS; 1997.

Chevallier A. The Encyclopedia of Medicinal Plants. DK Publishing; New York, NY; 1996.

Murray MT. The Healing Power of Herbs. 2nd Ed. Prima Publishing; Rocklin, CA; 1995.

Ellingwood F. American Materia Medica, Therapeutics and Pharmacognosy; Botanical Vol. II. Eclectic Medical Publications; Sandy, OR; 1994.

Felter HW. The Eclectic Materia Medica, Pharmacology and Therapeutics, Botanical Vol. 1. Eclectic Medical Publications; Sandy, OR; 1994.

Scalzo R. Naturopathic Handbook of Herbal Formulas. 3rd Ed. Kivaki Press; Durango, CO; 1994.

Ody P. The Complete Medicinal Herbal. Dorling Kindersley; New York, NY; 1993.

Stansbury JE. Botanical Medicines Acting on the Respiratory System. Preparatory Manuscript; Battleground, WA; 1992.

Stansbury JE. Pharmacognosy for the Herbal Practitioner. Preparatory Manuscript; Battleground, WA; 1992.

Thomas L. 10 Essential Herbs. Hohm Press; Prescott, AZ; 1992.

Weiss RF. Herbal Medicine. Beaconsfield Publishers LTD; Beaconsfield, England; 1991.

Hoffman D. The New Holistic Herbal. Element Inc; Rockport, MA; 1991.

Mabey R, et al. The New Age Herbalist. Collier Books, Macmillan Publishing Company; New York, NY; 1988. England;1988.

Tyler VE, et al. Pharmacognosy. 9th Ed. Lea & Febiger; Philadelphia, PA; 1988.

Wren RC. Potter's New Cyclopaedia of Botanical Drugs and Preparations. The C.W. Daniel Company Limited; Essex; 1988

Carr A, et al. Rodale's Illustrated Encyclopedia of Herbs. Rodale Press; Emmaus, PA; 1987.

Mowrey DB. The Scientific Validation of Herbal Medicine. Keats Publishing, Inc.; New Canaan, CT; 1986.

Beyer P. The Master Book of Herbalism. Phoenix Publishing; Custer, WA; 1984.

Goodenough J. Dr. Goodenough's Home Cures & Herbal Remedies. Avenel Books; New York, NY; 1982.

Millspaugh CF. American Medicinal Plants. Dover Publications, Inc.; New York, NY; 1974.

Grieve M. A Modern Herbal. Vol. I & II; Dover Publications, Inc.; New York, NY; 1971.


Homeopathy References


Morrison R.Desktop Guide to Keynotes and Confirmatory Symptoms.Hahnemann Clinic Publishing; Albany, CA; 1993.

Murphy R.Homeopathic Medical Repertory.Hahnemann Academy of North America; Pagosa Springs, CO; 1993.

Phatak SR. A Concise Repertory of Homoeopathic Medicines. B. Jain Publishers Pvt. Ltd.; New Delhi, India; 1992.

Kruzel T. The Homeopathic Emergency Guide.North Atlantic Books; Berkeley, CA; 1992.

Kent JT. Repertory of the Homeopathic Materia Medica.B. Jain Publishers (P) LTD; New Delhi, India; 1991.

Boericke W. Materia Medica with Repertory, 9th Ed..Boericke & Tafel, Inc.; Santa Rosa, CA; 1927.


Other Treatment References


Heavy Metal Chelation

Tuthill RW. "Hair lead levels related to children's classroom attention-deficit behavior." Archives of Envir Health. 1996;May/June,51(3):214-220.

Kahn CA, et al. "Lead screening children with attention deficit hyperactivity disorder and developmental delay." Clin Pediatrics. September,1995;498-501.

Howard JMH. "Clinical import of small increases in serum aluminum." Clin Chem. 1984;30(10):1722-1723.

Gittelman R, Eskenazi B. "Lead and hyperactivity revisited: an investigation of nondisadvantaged children." Arch Gen Psychiatry. August,1983;40:827-833.


Television and Flourescent Lights

Christakis DA, et al. "Early television exposure and subsequent attentional problems in children." Pediatrics. April,2004;113(4):708-713.

Marz RB. Medical Nutrition from Marz, 2nd ed. Omni Press; Portland, OR; 1997:315.


Thyroid Test

Weiss RE, et al. "Attention-deficit hyperactivity disorder and thyroid function." J Ped. 1993;123:539-545.

Hauser P, et al. "Attention deficit-hyperactivity disorder in people with generalized resistance to thyroid hormone." New Eng J Med. April8,1993;328(14):997-1001.

"Hyperactivity linked to gene defect." Med Trib. May21,1992;3.

Copyright 1998 - 2008 by L. Vicky Crouse, ND and James S. Reiley, ND. All rights reserved (ISSN 1527-0661).