Below are supplemental abstracts and references of research that support the conclusions on the treatment for Eczema

. Diet and Nutrition References


Food Allergies

Gore C, Custovic A. "Can we prevent allergy?" Allergy. 2004;59:151-161.

Fiocchi A, et al. "Dietary treatment of childhood atopic eczema/dermatitis syndrome (AEDS)." Allergy. 2004;59(Suppl 78):78-85.

Borok G. "Eczema and foods." SAMJ. February 2003;93(2):118-119.

Fiocchi A, et al. "Primary dietary prevention of food allergy." Ann Allergy Asthma Immunol. July 2003;91:3-13.

Chandra RK. "Food hypersensitivity and allergic diseases." Eur J Clin Nutr. 2002;56(Suppl 3):S54-S56.

Ellman-Grunther L, et al. "Atopic dermatitis and foods." Atopic Dermatitis. 2002:18;375-400.

Novembre E, Vierucci A. "Milk allergy/intolerance and atopic dermatitis in infancy and childhood." Allergy. 2001;56(Suppl. 67):105-108.

Worm M, et al. "Increased leukotriene production by food additives in patients with atopic dermatitis and proven food intolerance." Clin Exp Allergy. 2001;31:265-273.

Sicherer SH, et al. "Dose-response in double-blind, placebo-controlled oral food challenges in children with atopic dermatitis." J Allergy Clin Immunol. 2000;105:582-586.

Worcester S. "Test atopic children for food allergies." Skin and Allergy News. May,2000:44.

Varjonen E, et al. "Antigliadin IGE-indicator of wheat allergy in atopic dermatitis." Allergy. 2000;55:386-391.

Ikeda I. "Tofu-induced urticarial contact dermatitis." Arch Dermatol. January,2000;136:127-128.

Jones SM. "The role of food allergy and other allergic disease in atopic dermatitis." Clin Rev Allergy Immunol. 1999;17:293-321.

Sicherer SH, et al. "Food hypersensitivity and atopic dermatitis: pathophysiology, epidemiology, diagnosis, and management." J Allergy Clin Immunol. 1999;104(3 part 2):S114-S122.

Isolauri E, et al. "Breast-feeding of allergic infants." J Pediatr. January,1999;134(1):27-32.

Goldman AS, "Association of atopic diseases with breast-Feeding: food allergens, fatty acids, and evolution." J Pediatr. January,1999;134(1):5-7.

Burks AW, et al. "Atopic dermatitis and food hypersensitivity reactions." J Pediatr. 1998;132:132-136.

Howarth PH. "Is allergy increasing? - early life influences." Clin Exp Aller. 1998;28(Suppl. 6):2-7.

Atherton DJ. "Diet and atopic eczema." Clin Aller. 1998;18:215-228.

Resano A, et al. "Atopic dermatitis and food allergy." Invest Allergol Clin Immunol. September-October,1998;8(5):271-276.

Carpi J. "Atopy linked to food allergies in children, teens." Skin Aller News. December,1996.

Reekers R, et al. "The role of circulating food antigen-specific lymphocytes in food allergic children with atopic dermatitis." Br J Dermatol. 1996;135:935-941.

Bardare M, et al. "Influence of dietary manipulation on incidence of atopic disease in infants at risk." Ann Aller. October,1993;71:366-371.

Caffarelli C, et al. "Elimination diet and intestinal permeability in atopic eczema: a preliminary study." Clin Exp Aller. 1993;23:28-31.

Broberg A, et al. "Elimination diet in young children with atopic dermatitis." Acta Derm Venereol. 1992;72:365-369.

Sampson HA, Scanlon SM. "Natural history of food hypersensitivity in children with atopic dermatitis." J Pediatr. 1989;115;23-27.

Sampson HA, et al. "Spontaneous release of histamine from basophils and histamine-releasing factor in patients with atopic dermatitis and food hypersensitivity." N Engl J Med. July27,1989;321(4):228-232.

Burks AW, et al. "Atopic dermatitis: clinical relevance of food hypersensitivity reactions." J Pediatr. 1988;113:447-451.

Sampson HA, McCaskill CC. "Food hypersensitivity and atopic dermatitis: evaluation of 113 patients." J Pediatr. November,1985;107(5):669-675.

Munkvad M, et al. "Antigen-free diet in adult patients with atopic dermatitis." Acta Derm Venereol. 1984;64:524-528.

Sampson HA. "Role of immediate food hypersensitivity in the pathogenesis of atopic dermatitis." J Aller Clin Immunol. May,1983;71(5):473-480.

Hill DJ, Lynch BC. "Elemental diet in the management of severe eczema in childhood." Clin Aller. 1982;12:313-315.

Juto P, et al. "Treatment of infantile atopic dermatitis with a strict elimination diet." Clin Aller. 1978;8:493-500.

Atherton DJ, et al. "A double-blind controlled crossover trial of an antigen-avoidance diet in atopic eczema." Lancet. February 25,1978;1:401-403.

Matthew DJ, et al. "Prevention of eczema." Lancet. February12,1977;8007:321-324.

Livingood CS, Pillsbury DM. "Specific sensitivity to foods as a factor in various types of eczematous dermatitis." Arch Dermatol Syphilol. July-Dec,1949;60:1090-1115.


Trans Fatty Acids

Weiland SK, et al. "Intake of trans fatty acids and prevalence of childhood asthma and allergies in Europe." Lancet. June12,1999;353:2040-2041.


Vitamin and Mineral References


Vitamin A

Stoesser AV, Nelson LS. "Synthetic vitamin A in treatment of eczema in children." Ann Aller. Nov-Dec,1952:703-704.

Di Sant'Agnese PA, Larkin V deP. "Vitamin A absorption in infantile eczema." Proc Soc Exp Biol Med. 1943;52:343.

Gross P. "Nummular eczema: its clinical picture and successful therapy." Arch Dermatol Syphilol. 1941;44:1060-1077.


Vitamin C

Leveque N, et al. "High iron and low ascorbic acid concentrations in the dermis of atopic dermatitis patients." Dermatol. 2003;207:261-264.

Kline G, et al. "Ascorbic acid therapy for atopic dermatitis." J Aller Clin Immunol. 1989;83(1):196(#99).


Vitamin E and Selenium

Fogarty A, et al. "Dietary vitamin E, IgE concentrations, and atopy." Lancet. November4,2000;356:1573-1574.

Olson PE, et al. "Oral vitamin E for refractory hand dermatitis." Lancet. March12,1994;343:672-673.

Juhlin L, et al. "Blood glutathione peroxidase levels in skin diseases: effect of selenium and vitamin E treatment." Acta Derm Venereol (Stockh). 1982;62:211-14.


Zinc

Grace ND, et al. "Evaluation of intraruminal devices for combined facial eczema control and trace element supplementation in sheep." N Z Vet J. 1997;45:236-238.

David TJ. "Serum levels of trace metals in children with atopic eczema." Br J Dermatol. 1990;122:485-9.

Di Toro R, et al. "Zinc and copper status of allergic children." Acta Paediatr Scand. 1987;76:612-617.

David TJ, et al. "Low serum zinc in children with atopic eczema." Br J Dermatol. 1984;111:597-601.


Supplement References


Omega-3 Fatty Acids

Mayser P, et al. "A double-blind, randomized, placebo-controlled trial of n-3 versus n-6 fatty acid-based lipid infusion in atopic dermatitis." JPEN. 2002;26:151-158.

Barth GA, et al. "Food intake of patients with atopic dermatitis." Eur J Dermatol. May-June 2001;11(3):199-202.

Soyland E, et al. "Dietary supplementation with very long-chain omega-3 fatty acids in patients with atopic dermatitis. A double-blind, multi-center study." Br J Dermatol. 1994;130:757-764.

Bjorneboe A, et al. "Effect of dietary supplementation with eicosapentaenoic acid in the treatment of atopic dermatitis." Br J Dermatol. 1987;117:463-469.

Galland L. "Increased requirements for essential fatty acids in atopic individuals: a review with clinical descriptions." J Am Col Nutr. 1986;5:213-228.

Hansen AE, et al. "Eczema and essential fatty acids." Am J Dis Child. January,1947;73(1):1-18.

Hansen AE. "Serum lipid changes and therapeutic effects of various oils in infantile eczema." Proc Soc Exp Biol Med. 1933;31:160-163.


Omega-6 Fatty Acids

Horrobin DF. "Essential fatty acid metabolism and its modification in atopic eczema." Am J Clin Nutr. 2000;71(Suppl):367S-372S.

Yang B, et al. "Effect of dietary supplementation with sea buckthorn (Hippophae rhamnoides) seed and pulp oils on the fatty acid composition of skin glycerophospholipids of patients with atopic dermatitis." J Nutr Biochem. June,2000;11:338-340.

Horrobin DF. "Omega-6 fatty acids and atopic eczema." Medicinal Fatty Acids in Inflammation. 1998:55-64.

Hederos AC, Berg A. "Epogam evening primrose oil treatment in atopic dermatitis and asthma." Arch Dis Child. 1996;75:494-497.

Stewart JC, et al. "Treatment of severe and moderately severe atopic dermatitis with evening primrose oil (Epogam) a multi-centre study", J Nutr Med. 1991;2:9-15.

Horrobin DF, Stewart C. "Evening primrose oil in atopic eczema." Lancet. April7,1990;335:864-865.

Morse PF, et al. "Meta-analysis of placebo-controlled studies of the efficacy of Epogam in the treatment of atopic eczema. Relationship between plasma essential fatty acid changes and clinical response." Br J Dermatol. 1989;121:75-90.

Schalin-Karrila M, et al. "Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins." Br J Dermatol. 1987;117:11-19.

Manku MS, et al. "Reduced levels of prostaglandin precursors in the blood of atopic patients: defective delta-6-desaturase function as a biochemical basis for atopy." Prostaglandins Leukot Med. 1982;9:615-628.

Wright S, Burton JL. "Oral evening-primrose-seed oil improves atopic eczema." Lancet. November20,1982;2:1120.

Lovell CR, et al. "Treatment of atopic eczema with evening primrose oil." Lancet. January31,1981:278.


Hydrochloric Acid

Rappaport EM. "Achlorhydria: associated symtoms and response to hydrochloric acid." N Engl J Med. 1955;252:802-5.

Allison JR. "The relation of hydrochloric acid and vitamin B complex deficiency in certain skin diseases." South Med J. April,1945;38(4):235-241.


Quercetin

Nikaido T, et al. "Inhibitors of cyclic AMP phosphodiesterase in medicinal plants." J Med Plant Res. 1981;43:18-23.


Digestive Enzymes

Jackson P, et al. "Intestinal permeability in patients with eczema and food allergies." Lancet. 1981;1:1285.


Acidophilus and Bifidus

Abrahamsson TR, et al. "Probiotics in prevention of IgE-associated eczema: A double-blind, randomized, placebo-controlled trial." J Aller Clin Immunol. March7,2007.

Passeron T, et al. "Prebiotics and synbiotics: two promising approaches for the treatment of atopic dermatitis in children above 2 years." Allergy. 2006;61(4):431-7.

Skin and Allergy News. "Two probiotics help infants who have eczema, cow's milk allergy." November,2003:27.

Kalliomaki M, et al. "Probiotics and prevention of atopic disease: 4-year follow-up of a randomised placebo-controlled trial." Lancet. May31,2003;361:1869-1870.

Endres W. "Probiotics in the prevention of intestinal diseases in infancy." Monatsschr Kinderheilkd. 2003;151(Suppl 1):S24-S26.

"Two probiotics help infants who have eczema, cow's milk allergy." Skin Allergy News. November,2003:27.

Kirjavainen PV, et al. "Probiotic bacteria in the management of atopic disease: underscoring the importance of viability." JPGN. February,2003;36(2):223-227.

Laiho K, et al. "Inventing probiotic functional foods for patients with allergic disease." Ann Allergy Asthma Immunol. December,2002;86(Suppl 1):75-82.

Bienenstock J, et al. "Probiotics in the management and prevention of atopy." Clin Rev Allergy Immunol. 2002;22:275-285.

Kalliomaki M, et al. "Probiotics in primary prevention of atopic disease: a randomised placebo-controlled trial." Lancet. 2001;357:1076-1079.

Goldin BR. "Health benefits of probiotics." Br J Nutr. 1998;80(Suppl.2):S203-S207.


Botanical References


Glycyrrhiza glabra

Sheehan MP, et al. "A controlled trial of traditional chinese medicinal plants in widespread non-exudative atopic eczema." Br J Dermatol. 1992;126:179-84.

Teelucksingh S, et al. "Potentiation of hydrocortisone activity in skin by glycyrrhetinic acid." Lancet. May5,1990;335:1060-1063.

Evans FQ. "The rational use of glycyrrhetinic acid in dermatology." Br J Clin Prac. April,1958;12(4):269-274.


Ginkgo biloba

Amellal M, et al. "Inhibition of mast cell histmine release by flavonoids and bioflavonoids." Planta Med. 1985;51:16-20.


Arctium lappa

Brown DJ, Dattner AM. "Phytotherapeutic approaches to common dermatologic conditions." Arch Dermatol. November,1998;134:1401-1404.


Trifollium pratense, Taraxacum officinale, Smilax sarsaparilla, Urtica urens, Medicago sativa

Mitchell WA. Plant Medicine. Preparatory Manuscript; Seattle, WA; 2000.

Tilgner S. Herbal Medicine-From the Heart of the Earth. Wise Acres Press, Inc.; Creswell, OR; 1999.

Ogletree RL, Rischer RG. Physician's and Pharmacist's Guide to the Top 10 Scientifically Proven Natural Products. Natural Source Digest; 2nd Ed. Brandon, MS; 1997.

Chevallier A. The Encyclopedia of Medicinal Plants. DK Publishing; New York, NY; 1996.

Murray MT. The Healing Power of Herbs. 2nd Ed. Prima Publishing; Rocklin, CA; 1995.

Ellingwood F. American Materia Medica, Therapeutics and Pharmacognosy; Botanical Vol. II. Eclectic Medical Publications; Sandy, OR; 1994.

Felter HW. The Eclectic Materia Medica, Pharmacology and Therapeutics, Botanical Vol. 1. Eclectic Medical Publications; Sandy, OR; 1994.

Scalzo R. Naturopathic Handbook of Herbal Formulas. 3rd Ed. Kivaki Press; Durango, CO; 1994.

Ody P. The Complete Medicinal Herbal. Dorling Kindersley; New York, NY; 1993.

Stansbury JE. Botanical Medicines Acting on the Respiratory System. Preparatory Manuscript; Battleground, WA; 1992.

Stansbury JE. Pharmacognosy for the Herbal Practitioner. Preparatory Manuscript; Battleground, WA; 1992.

Thomas L. 10 Essential Herbs. Hohm Press; Prescott, AZ; 1992.

Weiss RF. Herbal Medicine. Beaconsfield Publishers LTD; Beaconsfield, England; 1991.

Hoffman D. The New Holistic Herbal. Element Inc; Rockport, MA; 1991.

Mabey R, et al. The New Age Herbalist. Collier Books, Macmillan Publishing Company; New York, NY; 1988. England;1988.

Tyler VE, et al. Pharmacognosy. 9th Ed. Lea & Febiger; Philadelphia, PA; 1988.

Wren RC. Potter's New Cyclopaedia of Botanical Drugs and Preparations. The C.W. Daniel Company Limited; Essex; 1988

Carr A, et al. Rodale's Illustrated Encyclopedia of Herbs. Rodale Press; Emmaus, PA; 1987.

Mowrey DB. The Scientific Validation of Herbal Medicine. Keats Publishing, Inc.; New Canaan, CT; 1986.

Beyer P. The Master Book of Herbalism. Phoenix Publishing; Custer, WA; 1984.

Goodenough J. Dr. Goodenough's Home Cures & Herbal Remedies. Avenel Books; New York, NY; 1982.

Millspaugh CF. American Medicinal Plants. Dover Publications, Inc.; New York, NY; 1974.

Grieve M. A Modern Herbal. Vol. I & II; Dover Publications, Inc.; New York, NY; 1971.


Homeopathy References


Morrison R.Desktop Guide to Keynotes and Confirmatory Symptoms.Hahnemann Clinic Publishing; Albany, CA; 1993.

Murphy R.Homeopathic Medical Repertory.Hahnemann Academy of North America; Pagosa Springs, CO; 1993.

Phatak SR. A Concise Repertory of Homoeopathic Medicines. B. Jain Publishers Pvt. Ltd.; New Delhi, India; 1992.

Kruzel T. The Homeopathic Emergency Guide.North Atlantic Books; Berkeley, CA; 1992.

Kent JT. Repertory of the Homeopathic Materia Medica.B. Jain Publishers (P) LTD; New Delhi, India; 1991.

Boericke W. Materia Medica with Repertory, 9th Ed..Boericke & Tafel, Inc.; Santa Rosa, CA; 1927.


Other Treatment References


Candida albicans

Savolainen J, et al. "Candida albicans and atopic dermatitis." Clin Exp Allergy. 1993;23:332-9.


Stress

Kodama A, et al. "Effect of stress on atopic dermatitis: investigation in patients after the Great Hanshin Earthquake." J Aller Clin Immunol. July,1999;104(1):173-176.

Munzel K and Schandry R. "Atopic eczema psychophysiological reactivity under standard stress." Hautarzt. 1990;41:601-611.


Mercury Toxicity

Adachi A, et al. "Mercury-induced nummular dermatitis." J Am Acad Dermatol. August,2000;43(2 part 2):383-385.

Copyright 1998 - 2008 by L. Vicky Crouse, ND and James S. Reiley, ND. All rights reserved (ISSN 1527-0661).