Below are supplemental abstracts and references of research that support the conclusions on the treatment for Menopause

. Diet and Nutrition References


Low Fat, High Fiber, Vegetarian-Based Diet

Juntunen KS, et al. "High-fiber rye bread and insulin secretion and sensitivity in healthy postmenopausal women." Am J Clin Nutr. 2003;77:385-391.

Fowke JH, et al. "Brassica vegetable consumption shifts estrogen metabolism in healthy postmenopausal women." Cancer Epidemiol Biomarkers Prev. August,2000;9:773-779.

Haggans CJ, et al. "The effect of flaxseed and wheat bran consumption on urinary estrogen metabolites in premenopausal women." Cancer Epidemiol Biomarkers Prev. July,2000;9:719-725.

Nagata C, et al. "Association of diet with the onset of menopause in Japanese women." Am J Epidemiol. 2000;152(9):863-867.

Salamone LM, et al. "Effect of a lifestyle intervention on bone mineral density in premenopausal women: a randomized trial." Am J Clin Nutr. 1999;70:97-103.

Barr SI. "Vegetarianism and menstrual cycle disturbances: is there an association?" Am J Clin Nutr. 1999;70(Suppl.):549S-554S.

Hudson T. Gynecology and Naturopathic Medicine. TK Publications; Aloha, OR; 1994:10-1.


Dairy Products

Honkanen R, et al. "Does lactose intolerance predispose to low bone density? A population-based study of perimenopausal Finnish women." Bone. 1996;July,19(1):23-28.


Alcohol

Sellers TA, et al. "Dietary folate intake, alcohol, and risk of breast cancer in a prospective study of postmenopausal women." Epidemiol. July,2001;12(4):420-428.

Van Der Gaag MS, et al. "Moderate alcohol consumption and changes in postprandial lipoproteins of premenopausal and postmenopausal women: a diet-controlled, randomized intervention study." J Womens Health Gender-Based Med. 2000;9(6):607-616.

Torgerson DJ, et al. "Alcohol consumption may influence onset of the menopause." Br Med J. July19,1997;315:188.


Caffeine, Raw Foods

Fenster L, et al. "Caffeine consumption and menstrual function." Am J Epidemiol. 1999;149(6):550-557.

Balch JF, et al. Prescription for Nutritional Healing, 2nd ed. Avery Publishing Group; NY, NY; 1997:241.


Soybean Products

Gallagher JC, et al. "The effect of soy protein isolate on bone metabolism." Menopause. 2004;11(3):290-298.

Hudson T. "Nutritional influences on osteoporosis." The Female Patient. July,2004;29:38-42.

Chen Y-M, et al. "Beneficial effect of soy isoflavones on bone mineral content was modified by years since menopause, body weight, and calcium intake: a double-blind, randomized, controlled trial." Menopause. 2004;11(3):246-254.

Tice JA, et al. "Phytoestrogen supplements for the treatment of hot flashes: The Isoflavone Clover Extract (ICE) Study: a randomized controlled trial." JAMA. July9,2003;290(2):207-214.

Wu AH, et al. "Soy intake and other lifestyle determinants of serum estrogen levels among postmenopausal Chinese women in Singapore." Cancer Epidemiol Biomarkers Prev. September,2002;11:844-851.

Arjmandi BH, Smith BJ. "Soy isoflavones' osteoprotective role in postmenopausal women: mechanism of action." J Nutr Biochem. 2002;13:130-137.

Kritz-Silverstein D, Goodman-Gruen DL. "Usual dietary isoflavone intake, bone mineral density, and bone metabolism in postmenopausal women." J Women's Health Gender-Based Med. 2002;11(1):69-78.

Cook A, Pennington G. "Phytoestrogen and multiple vitamin/mineral effects on bone mineral density in early postmenopausal women: a pilot study." J Women's Health & Gender-Based Med. 2002;11(1):53-60.

Persky VW, et al. "Effect of soy protein on endogenous hormones in postmenopausal women." Am J Clin Nutr. 2002;75:145-153.

Gardner CD, et al. "The effect of soy protein with or without isoflavones relative to milk protein on plasma lipids in hypercholesterolemic postmenopausal women." Am J Clin Nutr. 2001;73:728-735.

Mei J, et al. "High dietary phytoestrogen intake is associated with higher bone mineral density in postmenopausal but not premenopausal women." J Clin Endocrinol Metab. 2001;86(11):5217-5221.

Wangen KE, et al. "Soy isoflavones improve plasma lipids in normocholesterolemic and mildly hypercholesterolemic postmenopausal women." Am J Clin Nutr. 2001;73:225-231.

Horiuchi T, et al. "Effect of soy protein on bone metabolism in postmenopausal Japanese women." Osteoporos Int;. 2000;11:721-724.

Alekel DL, et al. "Isoflavone-rich soy protein isolate attenuates bone loss in the lumbar spine of perimenopausal women." Am J Clin Nutr. 2000;72:844-852.

Wangen KE, et al. "Effects of soy isoflavones on markers of bone turnover in premenopausal and postmenopausal women." J Clin Endocrinol Metab. 2000;85(9):3043-3048.

Takatsuka N, et al. "Hypocholesterolemic effect of soymilk supplementation with usual diet in premenopausal normolipidemic Japanese women." Prev Med. 2000;31:308-314.

Xu X, et al. "Soy consumption alters endogenous estrogen metabolism in postmenopausal women." Cancer Epidemiol Biomarkers Prev. August 2000;9:781-786.

Greenwood S, et al. "The role of isoflavones on menopausal health: consensus opinion of the North American Menopause Society." Menopause. July-August,2000;7(4):215-229.

Washburn S, et al. "Effect of soy protein supplementation on serum lipoproteins, blood pressure, and menopausal symptoms in perimenopausal women." Menopause. Spring,1999;6(1):7-13.

Duncan AM, et al. "Soy isoflavones exert modest hormonal effects in premenopausal women." J Clin Endocrinol Metab. 1999;84:192-197.

Messina MJ. "Legumes and soybeans: overview of their nutritional profiles and health effects." Am J Clin Nutr. 1999;70(Suppl.):439S-450S.

Albertazzi P, et al. "Dietary soy supplementation and phytoestrogen levels." Obstet Gynecol. 1999;94:229-231.

Nestel PJ, et al. "Isoflavones from red clover improve systemic arterial compliance but not plasma lipids in menopausal women." J Clin Endocrinol Metab. 1999;84:895-898.

Jackson K. "Soy: nature's estrogen." PA Today. January,1999;28-33.

Woods MN, et al. "Effect of a dietary soy bar on menopausal symptoms." Am J Clin Nutr. 1998;68(Suppl.):1533S.

Albertazzi P, et al. "The effect of dietary soy supplementation on hot flushes." Obstet Gynecol. January,1998;91(1):6-11.

Humfrey CDN. "Phytoestrogens and human health effects: weighing up the current evidence." Nat Toxins. 1998;6:51-59.

Potter SM, et al. "Soy protein and isoflavones: their effects on blood lipids and bone density in postmenopausal women." Am J Clin Nutr. 1998;68(Suppl):1375S-1379S.

Gallagher JC, et al. "Effects of soy isoflavone intake on bone metabolism in postmenopausal women." Am J Clin Nutr. 1998;68(Suppl):1518S.

Cassidy A, et al. "Hormonal effects of phytoestrogens in postmenopausal women and middle-aged men." Am J Clin Nutr. 1998;68(Suppl):1531S.

Dalais FS, et al. "Dietary soy supplementation increases vaginal cytology maturation index and bone mineral content in postmenopausal women." Am J Clin Nutr. 1998;68(Suppl):1518S.

Eden J, et al. "Hormonal effect of isoflavones." Am J Clin Nutr. 1998;68(Suppl.):1532S.

Knight DC, Eden JA. "A review of the clinical effects of phytoestrogens." Obstet Gynecol. May,1996;87(5 part 2):897-904.

Bullock C. "Soybeans: An estrogen replacement alternative?" Fam Prac News. April6,1995;11.

Wilcox G, et al. "Estrogen effects of plant foods in postmenopausal women." Br Med J. October20,1990;301:905-906.


Vitamin and Mineral References


Vitamin B6, Vitamin B-Complex

Hudson T. Gynecology and Naturopathic Medicine. TK Publications; Aloha, OR; 1994:10-6.


Vitamin C

Vihtamaki T, et al. "Oral ascorbic acid increases plasma oestradiol during postmenopausal hormone replacement therapy." Maturitas. 2002;42:129-135.

Kuo S-M, et al. "Ascorbic acid status in postmenopausal women with hormone replacement therapy." Maturitas. 2002;41:45-50.

Morton DJ, et al. "Vitamin C supplement use and bone mineral density in postmenopausal women." J Bone Miner Res. 2001;16(1):135-140.

Sellers TA, et al. "Dietary folate intake, alcohol, and risk of breast cancer in a prospective study of postmenopausal women." Epidemiology. July 2001;12(4):420-428.

Hall SL, Greendale GA. "The relation of dietary vitamin C intake to bone mineral density: results from the PEPI Study." Calcif Tissue Intl. 1998;63:183-189.

Smith CJ. "Non-hormonal control of vasomotor flushing in menopausal patients." Chic Med. 1964(67):193-95.


Vitamin D

Braam LAJLM, et al. "Beneficial effects of vitamins D and K on the elastic properties of the vessel wall in postmenopausal women: a follow-up study." Thromb Haemost. 2004;91:373-380.

Malabanan AO, Holick MF. "Vitamin D and bone health in postmenopausal women." J Women's Health. 2003;12(2):151-156.

Nakamura K, et al. "Serum 25-Hydroxyvitamin D concentrations and related dietary factors in peri- and postmenopausal Japanese women." Am J Clin Nutr. 2000;71:1161-1165.

LeBoff MS. "Occult vitamin D deficiency in postmenopausal US women with acute hip fracture." JAMA. April 28. 1999;281(16):1505-1511.

Kyriakidou-Himonas M, et al. "Vitamin D supplementation in postmenopausal black women." J Clin Endocrinol Metab. 1999;84(11):3988-3990.

Krall EA, et al. "Effect of vitamin D intake on seasonal variations in parathyroid hormone secretion in postmenopausal women." N Eng J Med. December28, 1989;321:1777-1783.


Vitamin E

Koh KK, et al. "Vascular effects of estrogen and vitamin E therapies in postmenopausal women." Circulation. November2,1999;100:1851-1857.

Wander RC, et al. "Alpha-tocopherol influences in vivo indices of lipid peroxidation in postmenopausal women given fish oil." J Nutr. 1996;126:643-652.

Blatt MHG, et al. "Vitamin E and climacteric syndrome: failure of effective control as measured by menopausal index." Arch Intern Med. 1953;91:792.

Gozan HA. "The use of vitamin E in the treatment of menopause." NY State J Med. 1952;52:1289.

Harris PL. "Vitamin E: its role in the menopause." J Am Osteopath Assoc. 1951;50:586.

McLaren HC. "Vitamin E in the menopause." Br J Med. December17,1949;1378.

Finkler RS. "The effect of vitamin E in the menopause." J Clin Endocrinol. 1949;9:89.

Christy CJ. "Vitamin E in menopause: preliminary report of experimental and clinical study." Am J Obstet Gynecol. 1945;50:84.


Calcium

J Fam Pract. "Do calcium supplements prevent postmenopausal osteoporotic fractures?" March,2003;52(3):234.

Chiu KM. "Efficacy of calcium supplements on bone mass in postmenopausal women." J Gerontol:Med Sci. 1999;54A(6):M275-M280.

Bostick RM, et al. "Relation of calcium, vitamin D, and dairy food intake to ischemic heart disease mortality among postmenopausal women." Am J Epidemiol. 1999;149(2):151-161.

Storm D, et al. "Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial." J Clin Endocrinol Metab. 1998;83(11):3817-3825.

Devine A, et al. "A 4-year follow-up study of the effects of calcium supplementation on bone density in elderly postmenopausal women." Osteop Internat. 1997;7(1):23-28.

Kilgore C. "Calcium enhances antiresorptive drugs' effectiveness: Bone mass increases threefold, on average, when calcium is added to an HRT regimen." Fam Prac News. July15,1997;27(14):1-2.

Reid IR, et al. "Long-term effects of calcium supplementation on bone loss and fractures in postmenopausal women: a randomized controlled trial." Am J Med. April,1995;98(4):331-335.

Aloia JF, et al. "Calcium supplementation with and without hormone replacement therapy to prevent postmenopausal bone loss." Ann Int Med. January15,1994;120(2):97-103.

Dawson-Hughes B, et al. "A controlled trial of the effect of calcium supplementation on bone density in postmenopausal women." N Eng J Med. September27,1990;323:878-883.


Calcium, Vitamin D

Masse PG, et al. "Dietary macro- and micronutrient intakes of nonsupplemented pre- and postmenopausal women with a perspective on menopause-associated diseases." J Hum Nutr Dietet. 2004;17:121-132.

Baeksgaard L, et al. "Calcium and vitamin D supplementation increases spinal BMD in healthy, postmenopausal women." Osteoporos Int. 1998;8:255-260.

Dawson-Hughes B. "Calcium and vitamin D nutritional needs of elderly women." J Nutr. 1996;126:1165S-1167S.

"Calcium, vitamin D supplements can stabilize postmenopause bone loss." Geriat. July,1991;46(7):68.

Wu CH. "Current considerations of the menopause." Ann Clin Lab Sci. May-June,1985;15(3):219-228.


Magnesium

Choay P, et al. "Value of micronutrient supplements in the prevention or correction of disturbances accompanying the menopause." Rev Fr Gynecol Obstet. 1990;85(12):702-705.

Cohen, et al. "Infared spectroscopy and magnesium content of bone mineral in osteoporotic women." Israel J Med Sci. 1981;17:1123-1125.


Supplement References


Bioflavonoids

Clemetson CAB, et al. "Capillary strength and the menstrual cycle." Ann NY Acad Sci. 1962(93):277-300.


EFA

Watkins BA, et al. "Omega-3 polyunsaturated fatty acids and skeletal health." Exp Biol Med. 2001;226(6):485-497.

Johnson K. "HRT adjuncts include soy, flaxseed, fish oil." Fam Prac News. November1,1998:38.

Wander RC, et al. "Alpha-tocopherol influences in vivo indices of lipid peroxidation in postmenopausal women given fish oil." J Nutr. 1996;126:643-652.

Hudson T. Gynecology and Naturopathic Medicine. TK Publications; Aloha, OR; 1994:10-5.


Ovary and Uterus Glandulars

Hudson T. Gynecology and Naturopathic Medicine. TK Publications; Aloha, OR; 1994:10-1,10-2.

Stein J. "Objective demonstration of the organ-specific effectiveness of cellular preparations." In: Schmid F, ed; Cell Research and Cellular Therapy. Ott Publishers; Thoune (Switzerland); 1967:294-301.

Neumann KH. "The influence of tissue injections on experimental liver damage." In:Schmid F, ed; Cell Research and Cellular Therapy. Ott Publishers; Thoune (Switzerland); 1967:368-79.

Stein J. "Specific effect on implanted endocrine tissues." In:Schmid F, ed; Cell Research and Cellular Therapy. Ott Publishers; Thoune (Switzerland); 1967:340-67.


Dehydroepiandrostrone (DHEA)

Takayanagi R, et al. "Dehydroepiandrosterone (DHEA) as a possible source for estrogen formation in bone cells: correlation between bone mineral density and serum DHEA-sulfate concentration in postmenopausal women, and the presence of aromatase to be enhanced by 1,25-Dihydroxyvitamin D3 in human osteoblasts." Mech Ageing Dev. 2002;123:1107-1114.

Hackbert L, Heiman JR. "Acute dehydroepiandrosterone (DHEA) effects on sexual arousal in postmenopausal women." J Women's Health Gender-Based Med. 2002;11(2):155-162.

Lasco A, et al. "Metabolic effects of dehydroepiandrosterone replacement therapy in postmenopausal women." Eur J Endocrinol. 2001;145:457-461.

Genazzani AD, et al. "Oral dehydroepiandrosterone supplementation modulates spontaneous and growth hormone-releasing hormone-induced growth hormone and insulin-like growth factor-1 secretion in early and late postmenopausal women." Fertil Steril. August,2001;76(2):241-248.

Haden ST, et al. "Effect of age on serum dehydroepiandrosterone sulfate, IGF-1, and IL-6 levels in women." Calcif Tissue Int. 2000;66:414-418.

Villareal DT, et al. "Effects of DHEA replacement on bone mineral density and body composition in elderly women and men." Clin Endocrinol. 2000;53:561-568.

Baker B. "DHEA increases bone mineral density in women." Fam Prac News. November1,2000:24.

Gordon CM, et al. "DHEA and the skeleton (through the ages)." Endocrine. August,1999;11(1):1-11.

Mazza E, et al. "Dehydroepiandrosterone sulfate levels in women. Relationships with age, body mass index and insulin levels." J Endocrinol Invest. 1999;22:681-687.

Casson PR, et al. "Postmenopausal dehydroepiandrosterone administration increases free insulin-like Growth Factor-I and decreases high-density lipoprotein: a six-month trial." Fertil Steril. July,1998;70(1):107-110.


Melatonin

Bellipanni G, et al. "Effects of melatonin in perimenopausal and menopausal women: a randomized and placebo-controlled study." Exp Gerontol. 2001;36:297-310.

Wakatsuki A, et al. "Effects of short-term melatonin administration on lipoprotein metabolism in normolipidemic postmenopausal women." Maturitas. 2001;38:171-177.


Botanical References


Cimicifuga (Black Cohosh), Angelica (Dong Quai), Leonurus (Motherwort), Glycyrrhiza (Licorice)

Kligler B. "Black cohosh." Am Fam Physician. July1,2003;68(1):114-116.

Kronenberg F, Fugh-Berman A. "Complementary and alternative medicine for menopausal symptoms: a review of randomized, controlled trials." Ann Intern Med. November19,2002;137(10):805-813.

Jancin B, "Black cohosh, Vitex appear safe for menopause tx." Fam Prac News. August1,1999.

Wong AHC, et al. "Herbal remedies in psychiatric practice." Arch Gen Psychiatry. November,1998;55:1033-1044.

Lieberman S. "A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause." J Women's Health. 1998;7(5):525-529.

Scarbeck K. "Botanicals used in menopause." Fam Prac News. January15,1996;46.


Glycyrrhiza glabra, Leonurus cardiaca, Angelica sinensis, Arctium lappa, Vitex agnus castus, Cimicifuga racemosa

Liske E. "Therapeutic efficacy and safety of Cimicifuga racemosa for gynecologic disorders." Advances in Therapy. January/February,1998;15(1):45-53.

Mitchell WA. Plant Medicine. Preparatory Manuscript; Seattle, WA; 2000.

Tilgner S. Herbal Medicine-From the Heart of the Earth. Wise Acres Press, Inc.; Creswell, OR; 1999.

Ogletree RL, Rischer RG. Physician's and Pharmacist's Guide to the Top 10 Scientifically Proven Natural Products. Natural Source Digest; 2nd Ed. Brandon, MS; 1997.

Chevallier A. The Encyclopedia of Medicinal Plants. DK Publishing; New York, NY; 1996.

Murray MT. The Healing Power of Herbs. 2nd Ed. Prima Publishing; Rocklin, CA; 1995.

Ellingwood F. American Materia Medica, Therapeutics and Pharmacognosy; Botanical Vol. II. Eclectic Medical Publications; Sandy, OR; 1994.

Felter HW. The Eclectic Materia Medica, Pharmacology and Therapeutics, Botanical Vol. 1. Eclectic Medical Publications; Sandy, OR; 1994.

Scalzo R. Naturopathic Handbook of Herbal Formulas. 3rd Ed. Kivaki Press; Durango, CO; 1994.

Ody P. The Complete Medicinal Herbal. Dorling Kindersley; New York, NY; 1993.

Stansbury JE. Botanical Medicines Acting on the Respiratory System. Preparatory Manuscript; Battleground, WA; 1992.

Stansbury JE. Pharmacognosy for the Herbal Practitioner. Preparatory Manuscript; Battleground, WA; 1992.

Thomas L. 10 Essential Herbs. Hohm Press; Prescott, AZ; 1992.

Weiss RF. Herbal Medicine. Beaconsfield Publishers LTD; Beaconsfield, England; 1991.

Hoffman D. The New Holistic Herbal. Element Inc; Rockport, MA; 1991.

Mabey R, et al. The New Age Herbalist. Collier Books, Macmillan Publishing Company; New York, NY; 1988. England;1988.

Tyler VE, et al. Pharmacognosy. 9th Ed. Lea & Febiger; Philadelphia, PA; 1988.

Wren RC. Potter's New Cyclopaedia of Botanical Drugs and Preparations. The C.W. Daniel Company Limited; Essex; 1988

Carr A, et al. Rodale's Illustrated Encyclopedia of Herbs. Rodale Press; Emmaus, PA; 1987.

Mowrey DB. The Scientific Validation of Herbal Medicine. Keats Publishing, Inc.; New Canaan, CT; 1986.

Beyer P. The Master Book of Herbalism. Phoenix Publishing; Custer, WA; 1984.

Goodenough J. Dr. Goodenough's Home Cures & Herbal Remedies. Avenel Books; New York, NY; 1982.

Millspaugh CF. American Medicinal Plants. Dover Publications, Inc.; New York, NY; 1974.

Grieve M. A Modern Herbal. Vol. I & II; Dover Publications, Inc.; New York, NY; 1971.


Homeopathy References


Morrison R.Desktop Guide to Keynotes and Confirmatory Symptoms.Hahnemann Clinic Publishing; Albany, CA; 1993.

Murphy R.Homeopathic Medical Repertory.Hahnemann Academy of North America; Pagosa Springs, CO; 1993.

Phatak SR. A Concise Repertory of Homoeopathic Medicines. B. Jain Publishers Pvt. Ltd.; New Delhi, India; 1992.

Kruzel T. The Homeopathic Emergency Guide.North Atlantic Books; Berkeley, CA; 1992.

Kent JT. Repertory of the Homeopathic Materia Medica.B. Jain Publishers (P) LTD; New Delhi, India; 1991.

Boericke W. Materia Medica with Repertory, 9th Ed..Boericke & Tafel, Inc.; Santa Rosa, CA; 1927.


Other Treatment References


Exercise

Rice VM. "Effect of moderate-intensity exercise in alleviating menopausal symptoms." Menopause. 2004;11(4):372-374.

Chan K, et al. "A randomized, prospective study of the effects of tai chi chun exercise on bone mineral density in postmenopausal women." Arch Phys Med Rehabil. May,2004;85:717-722.

Miller LE, et al. "Bone mineral density in postmenopausal women: does exercise training make a difference?" Physician Sportsmed. February,2004;32(2):18-24.

McKechnie R, et al. "Association between self-reported physical activity and vascular reactivity in postmenopausal women." Atherosclerosis. 2001;159:483-490.

Moreau KL, et al. "Increasing daily walking lowers blood pressure in postmenopausal women." Med Sci Sports Exerc. 2001;33(11):1825-1831.

Damilakis J, et al. "Effect of lifetime occupational physical activity on indices of bone mineral status in healthy postmenopausal women." Calcif Tissue Intl. 1999;64:112-116.

Kelley GA. "Aerobic exercise and bone density at the hip in postmenopausal women: a meta-analysis." Preventive Med. 1998;27:798-807.

Study:Carroll L. "Exercise helped quell symptoms of menopause." Med Trib. April20,1995;20.


Smoking

Windham GC, et al. "Cigarette smoking and effects on menstrual function." Obstet Gynecol. January,1999;93(1):59-65.

Hopper JL, Seeman E. "The bone density of female twins discordant For tobacco use." N Eng J Med. February10,1994;330(6):387-392.

Midgette AS, Baron JA. "Cigarette smoking and the risk of natural menopause." Epidemiol. November,1990;1(6):474-480.


Estrogen Replacement

Banks E, et al. "Fracture incidence in relation to the pattern of use of hormone therapy in postmenopausal women." JAMA. May12,2004;291(18):2212-2220.

Rapp SR, et al. "Effect of estrogen plus progestin on global cognitive function in postmenopausal women: The Women's Health Initiative Memory Study: a randomized controlled trial." JAMA. May28,2003;289(20):2663-2672.

Zegura B, et al. "Double blind, randomized study of estradiol replacement therapy on markers of inflammation, coagulation and fibrinolysis." Atherosclerosis. 2003;168:123-129.

Cauley JA, et al. "The Women's Health Initiative Randomized Trial: effects of estrogen plus progestin on risk of fracture and bone mineral density" JAMA. October1,2003;290(13):1729-1738.

Waters DD, et al. "Effects of hormone replacement therapy and antioxidant vitamin supplements on coronary atherosclerosis in postmenopausal women: a randomized controlled trial." JAMA. November20,2002;288(19):2432-2440.

Rossouw JE, et al. "Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the women's health initiative randomized controlled trial." JAMA. July17,2002;288(3):321-332.

Hlatky MA, et al. "Quality-of-life and depressive symptoms in postmenopausal women after receiving hormone therapy: results from the heart and estrogen/progestin replacement study (HERS) trial." JAMA. February6,2002;287(5):591-597.

Madsen JS, et al. "Effect of long-term hormone replacement therapy on plasma homocysteine in postmenopausal women: a randomized controlled study." Am J Obstet Gynecol. July 2002;187(1):33-39.

Angerer P, et al. "Effect of postmenopausal hormone replacement on atherosclerosis in femoral arteries." Maturitas. 2002;41:51-60.

LeBlanc ES, et al. "Hormone replacement therapy and cognition: systematic review and meta-analysis." JAMA. March 21. 2001;285(11):1489-1499.

Hak AE, et al. "The effect of hormone replacement therapy on serum homocysteine levels in perimenopausal women: a randomized controlled trial." Atherosclerosis. 2001;158:437-443.

Mijatovic V, van der Mooren MJ. "Homocysteine in postmenopausal women and the importance of hormone replacement therapy." Clin Chem Lab Med. 2001;39(8):764-767.

Rice MM, et al. "Postmenopausal estrogen and estrogen-progestin use and 2-year rate of cognitive change in a cohort of older Japanese American women: the KAME Project." Arch Intern Med. June12,2000;160:1641-1649.

Shlipak MG, et al. "Estrogen and progestin, lipoprotein (A), and the risk of recurrent coronary heart disease events after menopause." JAMA. April12,2000;283(14):1845-1852.

Clemente C, et al. "Antioxidant effect of short-term hormonal treatment in postmenopausal women." Maturitas. 1999;31:137-142.

Shaywitz SE, et al. "Effect of estrogen on brain activation patterns in postmenopausal women during working memory tasks." JAMA. April7,1999;281(13):1197-1202.

Greendale GA, et al. "The menopause." Lancet. February13,1999;353:571-580.

Copyright 1998 - 2008 by L. Vicky Crouse, ND and James S. Reiley, ND. All rights reserved (ISSN 1527-0661).